Optics and the Brain (Brain)

1. Optics in the Human Central Nervous System and Peripheral Nerves
   • Functional near infrared spectroscopy (fNIRS)
   • Diffuse optical spectroscopy and tomography (DOS/DOT)
   • Diffuse correlation spectroscopy (DCS)
   • Wearable systems
   • Brain computer interfaces (BCI)
   • Intrasurgical brain optical imaging
   • Fiber-optic probes, spectroscopy and edoscopic imaging
   • Optical modulation of the human central nervous system
   • Retinal neuroscience
   • Speckle contrast
   • Vascular and metabolic modeling
   • Clinical applications
   • Coherence tomography, non-invasive techniques, hyperspectral imaging
2. Rethinking Scan Patterns and Shaping Light
   • Light sheet microscopy
   • Wavefront engineering
   • Adaptive optics
   • Structured illumination
   • Temporal focusing
   • Non-gaussian beam shaping
   • Holography
   • Combining light sheet micro with microlaser spectro
3. Structural and Super-Resolution Techniques
   • Resolution improvement techniques
   • Fluorophores design and optimism
   • Use of super-resolution
   • Particle tracking
   • Molecular and biophysical processes
4. Analyzing Circuitry, Network Function and Information Processing
   • Model systems for network studies
   • Hybrid theoretical-experimental approaches to network analysis
   • Models of network inference
   • Imaging strategies optimized for network analysis
   • Deciphering functions from activity data
   • Multiscale imaging of brain activity
   • Functional microscopy
5. Optogenetics, Genetic Encoding and Novel Probes
   • ​Optode and electrode hardware for excitation and/or recording​
   • Use of miniatrue microscopes with optogenetics
   • Genetically encoded calcium and voltage indicators
   • Novel forms of functional contrast
   • New genetic strategies for optogenetics
   • Modeling and overcoming scatter in optogenetics
   • Challenges of scaling up optogenetics to non-human primates
6. Scattering, Clearing and Wavefront Engineering
   • ​​Advances in light sheet microscopy
   • Novel techniques for in-vitro and in-vitro whole-brain imaging and actuation
   • Zebrafish, drosophila and similar small organisms
   • Clearing techniques and structural imaging, animal to human
   • Optical data management and analysis strategies
   • Adaptive optics strategies
7. Brain Physiology and Disease
   • ​​Application of optical spectroscopy and imaging systems to the study of the brain in both health and disease (i.e., Alzheimer's stroke, epilepsy, etc.)
   • Models of brain diseases and optical tools
   • Photothrombosis
   • Optical therapeutics
   • Photodynamic therapy
   • Neuromodulation strategies
8. Big Data Tools (Collection, Management, Reduction, Analysis)
   • ​​Rapid imaging strategies
   • Serial slices imaging
   • Large field-of-view and space-bandwidth microscopes
   • Compression strategies
   • Data management tools
   • Machine learning
   • Software tools and date formats
   • ML data augmentation; high density datasets
9. Optical Hybrids​​
   • Photoacoustics / optoacoustics
   • Acousto-optic approaches
   • Acoustic modulation of neural activity
   • Combined optical / PET / CT / MRI
   • Combined electrical/optical
   • Integrated photo acoustic, ultrasound and angiographic tomography (PAUSAT) and photothermal infrared microscopy